Valery Barstow from Fallout

Valery Barstow was meant to become overseer of Vault 88, but its construction had barely begun by the time the bombs fell. Barstow was already on-site and got stuck in the vault for more than 200 years, during which she turned into a ghoul. The only thing that kept her sane, and prevented her from turning feral, was her loyalty to Vault-Tec and their cause. She spent most of her life preparing vault experiments. Once saved by the Sole Survivor, she enlists their help in finishing Vault 88's cons