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Mouse Brain Matrix
von ogianatiempo
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# Description
A Mouse Brain Matrix allows to slice a mouse brain into coronal or sagital sections, enabling precise and reproducible removal of small brain regions biological experiments. These matrices are commercially available, but are expensive and designed for a defined species and age. Reproducibility is a hallmark of good science but usually involves high costs when designs and hardware are proprietary. Open science hardware allows for greater reproducibility while improving accessibility when materials are low cost and easy to obtain, such as in 3D-printable designs.
The cost of 3D printing is now within reach of many scientific laboratories allowing for rapid and inexpensive prototyping of custom laboratory equipment. We therefore aimed to produce a simple design that could be used to section brain tissue in a reliable and reproducible manner using freely available software and a consumer grade 3D printer.
We have designed a matrix for adult mouse brains from an MRI scan
A Mouse Brain Matrix allows to slice a mouse brain into coronal or sagital sections, enabling precise and reproducible removal of small brain regions biological experiments. These matrices are commercially available, but are expensive and designed for a defined species and age. Reproducibility is a hallmark of good science but usually involves high costs when designs and hardware are proprietary. Open science hardware allows for greater reproducibility while improving accessibility when materials are low cost and easy to obtain, such as in 3D-printable designs.
The cost of 3D printing is now within reach of many scientific laboratories allowing for rapid and inexpensive prototyping of custom laboratory equipment. We therefore aimed to produce a simple design that could be used to section brain tissue in a reliable and reproducible manner using freely available software and a consumer grade 3D printer.
We have designed a matrix for adult mouse brains from an MRI scan
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